TABLE 3.
Region | Density1 | Intensity2 |
---|---|---|
Superior colliculus | ++ | +/++3 |
Inferior colliculus | ++ | +/++ |
Tegmental nuclei | +++ | ++/+++ |
Pedunculopontine nucleus | +++ | +++ |
Red nucleus | ++++4 | +++ |
Substantia nigra | ||
Pars compacta | ++ | +++ |
Pars reticulata | ++ | ++/+++ |
Raphe nuclei | ||
Dorsal nucleus | ++ | +++/++++ |
Median nucleus | + | ++ |
Edinger-Westphal nucleus | +++ | +/++ |
Principal oculomotor nucleus |
+++ | +++ |
Darkschewitsch nucleus | ||
Nuclei of the trigeminal nerve |
||
Mesencephalic nucleus | ++++ | +++ |
Motor nucleus | ++++4 | +++ |
Principal sensory nucleus |
+++ | +/++ |
Spinal nucleus | ++ | +/++ |
Facial nucleus | ++++4 | +++ |
Vestibular nuclei | +++ | ++/+++ |
Cochlear nuclei | ||
Dorsal nucleus | ++ | ++ |
Ventral nucleus | ++ | +++ |
Vagus nucleus | ++++ | ++++ |
Hypoglossal nucleus | ++++ | +++ |
Solitary nucleus | +++ | +/++ |
Ambiguus nucleus | +++ | ++++ |
Locus coeruleus | +++ | ++++ |
Superior olive | +++ | +++ |
Inferior olive | +++ | ++/+++ |
Nuclei of lateral lemniscus |
+++ | +++ |
Nucleus of trapezoid body | ||
Medial nucleus | ++++ | ++++ |
Lateral nucleus | +++ | ++ |
Cerebellum | ||
Molecular layer | +++ | + |
Purkinje cell layer | ++++ | ++++ |
Granular cell layer | +++ | + |
Cerebellar nuclei | +++ | +++ |
Density values are based on the percentage of positive cells related to total cell number. −, no positive cells; −/+, occasional cells, <10%; +, low, 10–5%; ++, moderate, 25–50%; +++, dense, 50–75%; ++++, very dense, >75%.
Staining intensity: +, weakly positive; ++, moderately positive; +++, intensely positive; ++++, strongly intense.
Two scores are noted because the region contains cell populations with different labeling intensity.
All large, multipolar neurons were CRF1 immunoreactive.