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. Author manuscript; available in PMC: 2011 Aug 1.
Published in final edited form as: J Am Soc Mass Spectrom. 2010 Apr 24;21(8):1432–1445. doi: 10.1016/j.jasms.2010.04.004

Figure 2.

Figure 2

Schematic overview of general cross-linking and enrichment strategies. A) Cross-linking of a peptide using Azide-DSG; B) Cartoon structures of biotin-alkyne and biotin-phosphine (see detailed structures in Fig. 1); Enrichment strategies based on C) copper catalyzed click chemistry; D) Staudinger ligation.