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Oral clearance rate (CL/F, L/h/m2) for nelfinavir in children with the CYP2C19-681G>A genotypes in each race/ethnicity. Each circle represents nelfinavir CL/F in each subject with the CYP2C19-681-G/G (left), -G/A (heterozygous, middle), and -A/A (homozygous, right) in each race/ethnicity. The lines in the middle represent the median of CL/F for NFV.
