Table 3.
Sex-specific association of serum urate (SUA) and prevalence of coronary artery calcification (CAC) among persons without hypertension, renal insufficiency, or diabetes.
| SUA, mg/dl | p for Trend | |||||
|---|---|---|---|---|---|---|
| < 5 (ref) | ≥ 5 – < 6 | ≥ 6 – < 6.8 | ≥ 6.8 | |||
| Men | ||||||
| No HTN* | Prevalence. % | 38.7 | 33.6 | 30.8 | 42.2 | — |
| Adj. OR (95% CI) | 1.0 | 0.89 (0.45–1.74) | 0.68 (0.34–1.39) | 0.95 (0.44–2.06) | 0.8 | |
| No renal insufficiency | Prevalence, % | 42.0 | 44.4 | 40.9 | 46.9 | — |
| Adj. OR (95% CI) | 1.0 | 1.19 (0.67–2.11) | 0.85 (0.47–1.55) | 0.91 (0.49–1.70) | 0.4 | |
| No diabetes | Prevalence, % | 40.7 | 42.4 | 41.5 | 47.0 | — |
| Adj. OR (95% CI) | 1.0 | 1.01 (0.55–1.87) | 0.83 (0.45–1.56) | 0.91 (0.48–1.71) | 0.6 | |
| Women | ||||||
| No HTN* | Prevalence, % | 11.2 | 14.8 | 27.9 | 24.1 | — |
| Adj. OR (95% CI) | 1.0 | 0.52 (0.27–0.98) | 0.79 (0.33–1.87) | 0.51 (0.16–1.65) | 0.1 | |
| No renal insufficiency | Prevalence, % | 15.6 | 25.1 | 33.7 | 36.6 | — |
| Adj. OR (95% CI) | 1.0 | 0.87 (0.53–1.44) | 0.73 (0.39–1.36) | 0.78 (0.37–1.66) | 0.3 | |
| No diabetes | Prevalence, % | 14.8 | 24.2 | 35.6 | 35.6 | — |
| Adj. OR (95% CI) | 1.0 | 0.82 (0.52–1.29) | 0.92 (0.49–1.74) | 0.72 (0.32–1.58) | 0.4 | |
*
Additionally adjusted for mean arterial pressure. HTN: hypertension.