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. 2009 Oct 9;38(6):1624–1633. doi: 10.1093/ije/dyp306

Table 2.

Characteristics of 29 935 treatment-naive study patients at baseline and 6 months after the initiation of potent combination ART

Characteristic No. of patients (%) No. of deaths (%) Crude mortality rate per 100 person-years of follow-upa
Total 29 935 (100) 1134 (100) 0.95
Age at baseline (years)
    16–29 5081 (17) 79 (7) 0.4
    30–39 13 376 (45) 457 (40) 0.83
    40–49 7646 (26) 343 (30) 1.17
    ≥50 3832 (13) 255 (22) 1.75
Sex
    Males 21 773 (73) 931 (82) 1.05
    Females 8162 (27) 203 (18) 0.68
Risk group
    MSM 11 960 (40 388 (34) 0.76
    Heterosexuals 13 575 (45) 392 (35) 0.79
    IDUs 4400 (15) 354 (31) 1.95
Clinical CDC stage at baseline
    A/B 23 197 (77) 668 (59) 0.72
    C 6738 (23) 466 (41) 1.77
CD4 count (cells/µl) Baseline measurement
    <25 3007 (10) 219 (19) 1.84
    25–49 1913 (6) 123 (11) 1.64
    50–99 3088 (10) 170 (15) 1.4
    100–199 5849 (20) 229 (20) 1.06
    200–349 8635 (29) 226 (20) 0.71
    ≥350 7443 (25) 167 (15) 0.49
6-month measurement
    <25 442 (1) 101 (9) 7.41
    25–49 599 (2) 88 (8) 3.95
    50–99 1923 (6) 147 (13) 1.9
    100–199 5189 (17) 255 (22) 1.27
    200–349 8092 (27) 261 (23) 0.86
    ≥350 13 690 (46) 282 (25) 0.49
Plasma HIV-1 RNA level (copies/ml) Baseline measurement
    ≤500 (undetectable) 433 (1) 15 (1) 0.94
    501–9999 3373 (11) 89 (8) 0.67
    10 000–99 999 11 931 (40) 350 (31) 0.73
    ≥100 000 14 198 (47) 680 (60) 1.22
6-month measurement
    ≤500 (undetectable) 23 539 (79) 674 (59) 0.73
    501–9999 3287 (11) 165 (15) 1.14
    10 000–99 999 1984 (7) 142 (13) 1.83
    ≥100 000 1125 (4) 153 (13) 3.71

aCalculation of time at risk started at 6 months.