Table 1.
Inhibitors altering PV formation.
| Inhibitor | Host target | |
|---|---|---|
| POSITIVE EFFECT | ||
| SB-203580 | p38 MAPK | |
| SB-202190 | p38 MAPK | |
| NEGATIVE EFFECT | ||
| GF 109203X | PKC | |
| Ro 31-8220 | PKC | |
| Sphingosine | PKC | |
| Palmitoyl-dl-carnitine Cl | PKC | |
| Rottlerin | PKC δ | |
| Lavendustin A | EGFRK | |
| RG-14620 | EGFRK | |
| Tyrphostin AG 1478 | EGFRK | |
| BML-265 | EGFRK | |
| Tyrphostin 9 | PDGFRK | |
| AG-1296 | PDGFRK | |
| PP1 | Src family | |
| AG-879 | NGFRK | |
| H-89 | PKA | |
| KN-93 | CaMKII | |
| ML-7 | MLCK | |
| ML-9 | MLCK | |
| ZM 449829 | JAK-3 | |
| Indirubin-3′-monoxime | GSK-3β | |
| Kenpaullone | GSK-3β | |
| Pentamidine | PRL1 | |
| Gossypol | PP2B | |
CaMKII, calmodulin kinase II; EGFRK, epidermal growth factor receptor kinase; GSK-3β, glycogen synthase kinase-3β; JAK-3, janus associated kinase-3; MAPK, mitogen activated protein kinase; MLCK, myosin light chain kinase; NGFRK, neuronal growth factor receptor kinase; PDGFRK, platelet derived growth factor receptor kinase; PKA, protein kinase A; PKC, protein kinase C; PP2B, protein phosphatase 2B; PRL1, phosphatase of regenerating liver 1.