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. Author manuscript; available in PMC: 2011 Jun 21.
Published in final edited form as: J Proteome Res. 2010 May 7;9(5):2610–2618. doi: 10.1021/pr100054v

Figure 4. BCAN is upregulated in 1p/19q nondeleted versus 1p/ 19q codeleted WHO grade II oligodendrogliomas.

Figure 4

Equivalent amounts of proteins derived from individual whole cell lysates of each of the 1p/19q undeleted and 1p/19q codeleted WHO grade II oligodendrogliomas used for proteomic analysis were run on Western blots. The blots were probed with antibodies to BCAN (B6) and beta actin as a loading control. B6 antibody identifies both the full length isoforms (upper bands; ~150–160 kDa) and cleaved products (lower bands; ~90–100 kDa) of BCAN.32 Representative Western blots are shown with beta actin controls (lower panel). Quantification of signal intensities of cleaved BCAN normalized to beta actin using densitometry demonstrated significantly increased mean signal intensities in nondeleted versus deleted grade II oligodendrogliomas (p < 0.05).