Figure 2.

Immunohistochemical staining for MT-1A protein in bronchial epithelium. Left side micrographs reveal the expression of MT-1A in the basal cell layer of control group airway epithelium (arrow, A and C). Right side micrographs show MT-1A expression in SM-injured airway epithelium (B and D). Note the immunoreactivity of MT-A1 in the control group is higher and wider than in the SM-injured samples. In the high and same magnification the epithelium layer thickness in SM-injured is much thicker than control group (C and D).

Abbreviations: L, airway lumen; Bm, basement membrane; MT, metallothionein; SM, sulfur mustard.