Table 2.
Bioprosthesis | Company | Material and treatment | Key remarks |
---|---|---|---|
O’Brien valve | CryoLife | Porcine valve with GAH low-pressure fixation | Actuarial freedom from SVD 91% at 5 years and 44% at 10 years70 |
Toronto SPV valve | St Jude Medical | Porcine valve with GAH low-pressure fixation | Freedom from reoperation 75% ± 5% at 12 years40 |
Freestyle valve | Medtronic | Porcine aortic root with GAH zero-pressure fixation with amino oleic acid treatment | Actuarial freedom from SVD 97.0% ± 2.2% (subcoronary), 96.0% ± 4.5% (full root), and 90.9% ± 11.2% (root inclusion) at 10 years,23 but deteriorate thereafter68 |
Prima Plus valve | Edwards Lifesciences | Porcine aortic root with GAH low-pressure fixation and XenoLogiX anticalcification treatment | Actuarial survival rate 71.5% at 8 years and freedom from SVD 97.8% at 8 years25 |
Biocor stentless valve | St Jude Medical | Porcine valve sutured to a GAH-treated bovine pericardial conduit | Freedom from reoperation 98.9% ± 0.7% at 9 years18 |
Pericarbon freedom valve | Sorin Biomedica | Bovine pericarial valve composed of two sheets sutured together, GAH treated, and detoxificated with homocysteic acid | Freedom from valve-related death and reoperation 91% ± 4% and 94% ± 4% at 7 years No structural valve deterioration observed10 |
Super-stentless valve | Shelhigh | Porcine valve mounted on a superflexible ring with GAH and No-React anticalcification treatment | Possible contamination and malfuction warning by the US Food and Drug Administration71 |
3F Therapeutics stentless valve | ATS Medical | Equine pericardial tubular valve treated with bufferd formulation of GAH fixation | Large effective orifice area (1.7 cm2)11 |
Abbreviations: GAH, glutaraldehyde; SVD, structural valve deterioration.