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. 2001 Mar 20;98(7):4160–4165. doi: 10.1073/pnas.051626998

Figure 3.

Figure 3

VEGF IR and NADPH–diaphorase staining in neurons in scg of controls and newborn rats treated with NGF (1 and 8 days) and 6-OHDA + NGF (8 days) and density evaluation. Eight days of NGF treatment induces a significant increase in VEGF expression; a greater increase occurs after concomitant 6-OHDA and NGF administration. Single NGF administration strongly up-regulates NADPH–diaphorase staining, but the increase induced by 8 days of combined 6-OHDA and NGF treatment far exceeds that of NGF single administration. Statistical analysis: ANOVA and Dunnett's test; *, P < 0.05. (Bar = 100 μm.)