Figure 1. Effect of 5HD, administered at the time of sham/sepsis induction, on hemodynamics and survival in the rat.

The effect of 5HD on the, (A) rectal temperature, (B) survival and (C) Mean Arterial Pressure, MAP of the septic rats. Sham (N = 10), sepsis (N = 10); sepsis+5HD (N = 7). The values in the sepsis group at 48 and 72 hr include only two surviving animals.*P≤0.05 compared to the sham group and # P≤0.05 compared to the sepsis group at respective time points.