Table 2.

Mouse survival after infection with the indicated Salmonella strains.

Dose	χ3761 wild-type	χ9434 ΔpagP8	χ9732e ΔpagP81::PlpplpxE (m-lipid A)a	χ9485 ΔpagL7 ΔpagP8 ΔlpxR9	χ9705e ΔpagL7 ΔpagP81::PlpplpxE ΔlpxR9 (m-lipid A)
1× 103 CFU	4/5b	6/7	-	2/2	-
1× 104 CFU	2/5	3/7	-	6/7	-
1× 105 CFU	0/5	0/7	-	3/7	-
1× 106 CFU	-c	0/2	2/2	0/7	2/2
1× 107 CFU	-	-	7/7	-	7/7
1× 108 CFU	-	-	6/7	-	7/7
1× 109 CFU	-	-	3/7	-	7/7
LD50 (CFU)d	0.9 × 104	0.9 × 104	0.66 × 109	5.7 × 104	>1 × 109

^a1-monophosphoryl lipid A

^bSurvivors/total number of mice

^cDose not tested

^dLD₅₀ data were from probit analyses

^eSurviving mice were challenged with 1 × 10⁹ CFU of χ3761 thirty days after the initial inoculation. All challenged mice survived.