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. Author manuscript; available in PMC: 2012 Jul 11.
Published in final edited form as: Brain Res. 2011 May 19;1400:31–41. doi: 10.1016/j.brainres.2011.05.028

Figure 1.

Figure 1

Effect of chronic food restriction on CPP reinforced by cocaine (7.0 mg/kg, i.p). Mean (± S.E.M.) time spent (sec) in the cocaine- and saline-paired sides of the CPP apparatus during the preconditioning session, six subsequent post-conditioning test sessions, and a seventh test session conducted immediately after administration of a “priming” injection of cocaine (7.0 mg/kg, i.p.). The first CPP test was conducted 48 h after the final conditioning session. The seventh test, preceded by a cocaine prime, was conducted 48 h after the AL group had satisfied extinction criterion. #Time spent on the cocaine-paired side relative to the saline-paired side was greater, across feeding conditions, in the first CPP test (p<.0001). *Time spent on the cocaine-paired side relative to the saline-paired side was greater across all drug-free test sessions in the FR (p <.01) but not in the AL group. @In the seventh test, which was preceded by a cocaine prime, time spent on the cocaine-paired side relative to the saline-paired side was greater in FR (p<.025) but not in AL rats. nAL=9, nFR=10.