Table 3.
Allele and genotype frequencies in a case control cohort of patients with EC
| dbSNP identity | Genotype | No. of patients with EC (%) | No. of controls (%) | P value | P value after multivariate logistic regression | p value after multiple testing correction (Bonferroni method) | odds Ratio (%95 CI) | |
|---|---|---|---|---|---|---|---|---|
| rs10437048 | allele | C | 58(0.3766) | 1(0.0077) | 2.255×10-14 | 4.182×10-6 | 1.55610-12 | 0.012831 [0.001746~0.094278] |
| A | 96(0.7234) | 129(0.9923) | ||||||
| genotype | CC | 6(0.0779) | 0(0) | 2×10-14 | 4.182×10-6 | 1.556×10-12 | - | |
| CA | 46(0.5974) | 1(0.0154) | ||||||
| AA | 25(0.3247) | 64(0.9846) | ||||||
| rs41265997 | allele | A | 46(0.3333) | 5(0.0378) | 5.646×10-10 | 1.745×10-9 | 3.89×10-8 | 12.7 [4.857077~33.207214] |
| G | 92(0.6667) | 127(0.9622) | ||||||
| genotype | AA | 0(0) | 0(0) | 1.15×10-12 | 1.745×10-9 | 3.89×10-8 | - | |
| AG | 46(0.6667) | 5(0.0757) | ||||||
| GG | 23(0.3333) | 61(0.9243) |
67 controls & 83 cases observed