Table 5.

miR-17-92 target regions are commonly conserved in Chinese hamster ovary cells.

No.	Gene symbol	RefSeq accession	miR-17-92 seed family	Seed pos. in mouse 3’ UTR	Seed pairing Type	pCT score	Alignment	Percentage identity
1	APP	NM_007471.2	miR-17 family	726–732	7mer-m8	0.60		91.0
2	BCL2L11 (Bim)	NM_207680.2	miR-17 family	2107–2113	8mer	0.93		n/a
3	CCND1	NM_007631.2	miR-17 family	925–931	7mer-m8	0.87		100.0
4	CDKN1A (p21)	NM_007669.3	miR-17 family	436–442	7mer-m8	0.85		n/a
5	CTGF	NM_010217.1	miR-18 family	1023–1029	7mer-m8	0.39		100.0
6	E2F1	NM_007891.2	miR-17 family	469–475	7mer-m8	0.59		91.7
	E2F1	NM_007891.2	miR-17 family	984–990	7mer-m8	0.77		n/a
7	GAB1	NM_021356.2	miR-17 family	263–269	7mer-m8	0.68		n/a
8	HIF-1α	NM_010431.1	miR-17 family	975–981	7mer-m8	0.36		95.0
	HIF-1α	NM_010431.1	miR-18 family	304–310	7mer-m8	0.51		100.0
9	HIPK3	NM_005734.3	miR-25 family	118–124	7mer-m8	0.73		100.0
	HIPK3	NM_005734.3	miR-19 family	165–171	8mer	0.79		n/a
10	IRF1	NM_008390.1	miR-17 family	584–590	7mer-m8	0.44		100.0
11	ITCH	NM_008395.2	miR-17 family	1102–1108	7mer-m8	0.74		n/a
12	MAPK9	NM_016961.2	miR-17 family	361–367	7mer-m8	< 0.1		95.0
13	MAPK14	NM_011951.2	miR-19 family	1819–1825	8mer	0.39		n/a
14	MYLIP	NM_153789.3	miR-25 family	1200–1206	8mer	0.96		95.0
	MYLIP	NM_153789.3	miR-19 family	1314–1320	8mer	0.90		100.0
15	NCOA3	NM_008679.2	miR-17 family	588–594	8mer	0.95		95.0
16	PKD1. PKD2	NM_013630.2	miR-17 family	192–198	8mer	0.90		82.6
17	PTEN	NM_008960.2	miR-19 family	1236–1242	8mer	0.58		100.0
18	RB1	NM_009029.1	miR-17 family	844–850	7mer-m8	0.31		95.0
19	RB2/p130	NM_011250.2	miR-17 family	598–604	8mer	0.83		100.0
20	RUNX1	NM_009821.1	miR-17 family	1748–1756	7mer-m8	0.88		n/a
21	SOCS-1	NM_009896.2	miR-19 family	293–299	8mer	0.9		100.0
22	STAT3	NM_213659.2	miR-17 family	156–162	7mer-m8	0.56		96.0
23	TGFBR2	NM_009371.2	miR-17 family	298–304	8mer	0.96		95.0
24	THBS1	NM_011580.3	miR-19 family	1840–1846	7mer-1A	0.36		n/a
25	TSG101	NM_021884.3	miR-17 family	170–176	7mer-m8	< 0.1		100.0
26	VEGFA	NM_001025250.2	miR-17 family	109–115	7mer-m8	0.87		100.0