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. Author manuscript; available in PMC: 2012 Apr 22.
Published in final edited form as: Chem Biol. 2011 Apr 22;18(4):508–519. doi: 10.1016/j.chembiol.2011.01.019

Table 1. Analysis of coding sequences in pag.

Proteins highlighted in grey are homolgs of those known to be associated with cyanobactin biosynthesis in other systems.

Predicted Protein Best Cyanobactin Hit % Identity Predicted Function Organism
PagC AcyC 49% Unknown Anabaena sp. 90
PagB AcyB 78% Unknown Anabaena sp. 90
PagA AcyA and OscA 73% and 73% N-terminal protease Anabaena sp. 90 and Oscillatoria sp. PCC 6506
Orf1 None 70% Conserved Hypothetical Protein Oscillatoria sp. PCC 6506
Orf2 None 89% Conserved Hypothetical Protein Microcystis aeruginosa NIES-843
PagF AcyF 75% Prenyltransferase Anabaena sp. 90
Orf3 Acy-Orf5 81% Transposase Anabaena sp. 90
PagE7 AcyE 56% Precursor peptide (Prenylagaramide C) Anabaena sp. SYKE 844B
PagE6 AcyE 57% Precursor peptide (Prenylagaramide B) Anabaena sp. PH262
PagE5 AcyE 52% Precursor peptide Anabaena sp. PH262
PagE4 AcyE 38% Precursor peptide Anabaena sp. SYKE 816
Orf4 None 36% Conserved Hypothetical Protein Oscillatoria sp. PCC 6506
Orf5 None 54% Conserved Hypothetical Protein Microcystis aeruginosa NIES-843
Orf6 None 72% Conserved Hypothetical Protein Microcystis aeruginosa NIES-843
Orf7 None 74% Conserved Hypothetical Protein Microcystis aeruginosa NIES-843
PagE3 AcyE 71% Precursor peptide Anabaena sp. PH262
Orf8 None 71% Conserved Hypothetical Protein Nostoc punctiforme PCC 73102
Orf9 None 68% Conserved Hypothetical Protein Microcystis aeruginosa PCC 7806
Orf10 Acy-Orf5 77% Transposon Anabaena sp. 90
PagE2 AcyE 66%-N terminus Precursor peptide Anabaena sp. 202A1/35
Orf11 None 91% Conserved Hypothetical Protein Nostoc sp. PCC 7120
PagE1 AcyE 47% Precursor peptide Anabaena sp. PH262
PagG AcyG 70% C-terminal protease Anabaena sp. 90