FIG. 5.

Clinical example of reperfusion injury in the setting of reperfusion therapy. A 65-year-old woman presented with recurring episodes of right sided weakness and speech difficulties. (A) A CT perfusion image showed a large area of reduced perfusion to the left hemisphere (white arrow). (B) Cerebral angiography was performed and showed a severe stenosis of the left internal carotid artery (black arrow). (C) A carotid stent (dashed black arrow) was placed to revascularize the severe narrowing but was complicated with (D) an embolus to the left middle cerebral artery (black arrow). (E) A stent was implanted in the left middle cerebral artery (dashed black arrow) with successful reperfusion achieved at 60 min from the initial time of the embolus. (F) A large hemorrhage (dashed white arrow) was noted within a sizeable infarct despite rapid reperfusion of the iatrogenic embolus. The mechanism was likely reperfusion injury. (To see this illustration in color the reader is referred to the web version of this article at www.liebertonline.com/ars).