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. 2010 Aug 30;16(12):3727–3736. doi: 10.1089/ten.tea.2010.0234

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Copyright 2010, Mary Ann Liebert, Inc.

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FIG. 4. — Microcomputational analysis of the resultant heterotopic bone formation. (A, D) Three-dimensional surface renderings of the resultant heterotopic bone. (B, E) Cross-sectional slices through the new bone. (C, F) Corresponding radiograms. (A–F) The resultant mineralization of the muscle tissues after injection of AdBMP2-transduced cells (2500 VP/cell) encapsulated into PEGDA microspheres (A–C) or direct injection of unencapsulated AdBMP2-transduced cells (D–F). Both have a denser rim of bone, with a hollow interior structure, suggesting that the biomaterial did not alter bone patterning.