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. Author manuscript; available in PMC: 2011 Jun 22.
Published in final edited form as: Met Ions Life Sci. 2009 Jan 30;6:53–114. doi: 10.1039/BK9781847559159-00053

Figure 8. Intermodular contacts between His 759 and residues in the AdoMet-binding reactivation module of MetH.

Figure 8

Nε2 of His759 interacts with the AdoMet module directly through a hydrogen bond to Asp1093 and via a water-mediated hydrogen bond to Glu1069. Nδ1 of His759 forms a hydrogen bond with the amide of the propionamide side chain of ring B of the cobalamin (not shown). Adapted from 20.