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NMR-observed chemical shift changes in EIAV MA induced by binding to PIP2-C4 (A) and PIP2-C6 (B). The EIAV MA concentrations were 195 (A) and 130 μM (B). The PIP2:protein molar ratio is 1:1. Only fully isolated residues, 91 of 105, are presented for both data sets.