Table 5.

Amidine Synthesis via Aza-Claisen Rearrangement.

entry	ynamides	aminesa	amidine products	yield [%]b
1	8b		56	94
2	8d		57	58
3	8k		58	77
4	8a		59	≥95
5	8f		60	93

^aAll reactions utilized 3.0 equiv of the amine and were run in toluene [concn = 0.05 M] at 110 °C over 24 h except it was 48 h for entry 4.

^bIsolated yields.