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Study protocol (A) and GIRs during euglycemic-hyperinsulinemic clamps (B). Each subject was studied thrice randomly and CEU/MCE performed before and after 2-h euglycemic insulin clamp. Plasma glucose was measured every 5 min and GIR was adjusted to maintain euglycemia. AUC, area under the curve. *P < 0.007 vs. control.
