Table 1.
Mean demographic and cardiometabolic factors of individuals aged ≥40 years by peripheral neuropathy* and PVD† status, NHANES III, 2001–2004
| Total | Peripheral neuropathy | No peripheral neuropathy | P‡ | PVD | No PVD | P‡ | |
|---|---|---|---|---|---|---|---|
| Proportion (%) | 100 | 9.0 (0.7) | 91.0 (0.7) | 8.5 (0.8) | 91.5 (0.8) | ||
| Age (years) | 56.4 (0.3) | 63.2 (0.7) | 55.8 (0.4) | <0.0001 | 62.2 (1.2) | 55.4 (0.3) | <0.0001 |
| Sex (%) | |||||||
| Male | 47.9 (1.0) | 65.5 (3.1) | 46.2 (1.0) | <0.0001 | 37.6 (3.8) | 49.7 (1.2) | 0.01 |
| Female | 52.1 (1.0) | 34.5 (3.1) | 53.8 (1.0) | <0.0001 | 62.4 (3.8) | 50.3 (1.2) | 0.01 |
| Race/ethnicity (%) | |||||||
| White | 77.8 (2.2) | 78.8 (3.2) | 77.7 (2.2) | Reference | 75.0 (3.8) | 78.4 (2.1) | Reference |
| Black | 9.4 (1.2) | 11.5 (2.0) | 9.2 (1.2) | 0.04 | 15.1 (2.8) | 8.6 (1.1) | <0.0001 |
| Other | 12.8 (1.8) | 9.7 (2.6) | 13.1 (1.8) | 0.06 | 9.9 (26) | 12.9 (1.8) | 0.01 |
| Education (%) | |||||||
| Less than high school | 18.9 (1.0) | 22.2 (3.6) | 18.5 (1.0) | 0.7 | 27.6 (4.1) | 17.1 (1.1) | 0.4 |
| High school or equivalent | 25.7 (1.0) | 25.0 (3.6) | 25.8 (1.2) | Reference | 25.4 (3.1) | 25.9 (1.2) | Reference |
| More than high school | 55.4 (1.5) | 52.8 (4.8) | 55.7 (1.5) | 0.5 | 47.1 (3.5) | 57.0 (1.7) | 0.009 |
| Weight (kg) | 81.8 (0.5) | 88.3 (1.6) | 81.1 (0.5) | <0.0001 | 82.3 (1.6) | 81.6 (0.6) | 0.6 |
| Waist circumference (cm) | 99.0 (0.4) | 105.5 (0.9) | 98.4 (0.4) | <0.0001 | 102.5 (1.0) | 98.5 (0.4) | <0.0001 |
| BMI (kg/m2) | 28.5 (0.2) | 29.4 (0.4) | 28.4 (0.2) | 0.01 | 29.8 (0.6) | 28.3 (0.2) | 0.0009 |
| Glucose (mg/dL) | 105.6 (0.8) | 111.8 (2.4) | 105.0 (0.8) | 0.0005 | 110.2 (2.4) | 104.8 (0.8) | 0.002 |
| Diabetes (%) | 15.5 (0.9) | 23.6 (3.1) | 14.7 (1.0) | 0.003 | 21.2 (3.0) | 14.4 (0.9) | 0.008 |
| Lipid levels (mg/dL) | |||||||
| HDL cholesterol | 52.9 (0.7) | 50.3 (1.6) | 53.1 (0.7) | 0.2 | 53.3 (2.3) | 52.7 (0.7) | 0.8 |
| LDL cholesterol | 123.3 (1.2) | 117.4 (3.5) | 123.9 (1.1) | 0.05 | 119.9 (2.7) | 123.7 (1.2) | 0.2 |
| Triglycerides | 161.1 (5.8) | 187.0 (22.2) | 158.5 (5.4) | 0.05 | 167.2 (12.8) | 160.1 (6.2) | 0.5 |
| Blood pressure (mmHg) | |||||||
| Systolic | 127.6 (0.6) | 131.4 (1.7) | 127.2 (0.6) | 0.02 | 136.7 (1.5) | 126.2 (0.6) | <0.0001 |
| Diastolic | 72.6 (0.4) | 70.9 (1.1) | 72.8 (0.4) | 0.1 | 69.7 (1.0) | 73.2 (0.4) | <0.0001 |
| Hypertension (%) | 56.4 (1.5) | 66.9 (3.9) | 55.3 (1.6) | 0.007 | 76.3 (3.3) | 53.7 (1.6) | <0.0001 |
Data are means (SE) for continuous variables and percentage (SE) for categorical variables.
*Peripheral neuropathy defined as one or more insensate sites on either foot.
†PVD defined as an ABPI <0.90.
‡P values obtained from bivariate logistic regression. Statistical significance considered P value <0.05.