Figure 5. Increased phosphorylated PKCζ in membrane fractions in psoriasis plaques.
Whereas no consistent difference was demonstrated in phosphorylated PKCζ in the whole lysates or in the cytosolic fractions of psoriasis and their uninvolved skin (n = 6), the membrane fractions of psoriasis lesions (L) showed significant increase in phospho-PKCζ compared with their uninvolved counterparts (N). P < 0.01, Student’s t-test. Values are mean ± SD, error bar = 1 SD.