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. 2001 Mar 27;98(7):4221–4226. doi: 10.1073/pnas.071516798

Figure 6.

Figure 6

Influence of pendrin on JtCO2. Isolated CCD tubules from wild-type (Pds+/+) or pendrin-deficient (Pds−/−) mice were perfused in symmetric, HCOInline graphic/CO2-buffered solutions. tCO2 concentration was measured in collected perfusate samples in CCD tubules. Values measured for each tubules are given (see Table 1 for additional details). In wild-type mice, the JtCO2 was −2.6 ± 1.4 pmol/mm/min (n = 4); in pendrin-deficient mice, the JtCO2 was +2.7 ± 0.6 pmol/mm/min (n = 4, P < 0.05).