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Contribution of pendrin to bicarbonate secretion in the mouse CCD
| Mice | Number of tubules | Tubule length, mm | Collection rate, nl/mm/min | Bath pH | Total CO2
|
||
|---|---|---|---|---|---|---|---|
| Perfusate concentration, mM | Collected concentration, mM | Total CO2 Flux, pmol/mm/min | |||||
| Pds+/+ | 4 | .40 ± .03 | 1.90 ± .12 | 7.41 ± .03 | 24.8 ± 0.4 | 26.2 ± 0.6 | −2.6 ± 1.4 |
| Pds−/− | 4 | .37 ± .04 | 2.04 ± .14 | 7.45 ± .02 | 24.9 ± 1.0 | 23.6 ± 0.8 | +2.7 ± 0.6 |
