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Family pedigree of the FXTAS patient. There is family history of mental retardation in males, and psychiatric disease in females. Individual IV:3 also presents tremor. Individual IV:4 died in infancy and was never tested for FXS. FMR1 repeat lengths are available for individuals marked with an asterisk. Symbols with the black circle are obligatory carriers of a FMR1 expanded allele. An arrow indicates the proband. (N, normal repeat size).
