Table 10.
Top ranking co-occurring domains in novel yeast interactions.
| Domain Name A | Domain Name B | DOMINE | Number of sites |
|---|---|---|---|
| Actin-like | Retrotransposon Ty1 A, N-terminal | Known | 360 |
| Serine/threonine-protein kinase-like domain | Serine/threonine-protein kinase-like domain | Known | 221 |
| Protein kinase-like domain | Serine/threonine-protein kinase-like domain | Novel | 170 |
| Sugar/inositol transporter | Protein kinase-like domain | Novel | 106 |
| Ras GTPase | Serine/threonine-protein kinase-like domain | Known | 99 |
| Ras GTPase | Ras GTPase | Known | 95 |
| Ras GTPase | Small GTPase, Rho type | Known | 57 |
| ATPase, AAA-type, core | ATPase, AAA-type, core | Known | 56 |
| ATPase, AAA-type, core | ATPase, AAA-type, conserved site | Novel | 52 |
| Sugar/inositol transporter | Serine/threonine-protein kinase-like domain | Known | 51 |
Out of the 100 most frequently occurring domain pairs, 55% are reported in the DOMINE database.