Table 6.

Analysis of Top RA-SNPs for Association with AD in Combined Stage 1 and Age-Matched Stage 2.

Uncorrected Logistic Regression						Regression Corrected for Age, Sex and APOE
CHR	SNP	OR	L95	U95	P	OR	L95	U95	P
21	rs2837960	1.239	1.083	1.418	0.002	1.199	1.032	1.392	0.018
18	rs2002842	1.056	0.948	1.178	0.323	1.050	0.931	1.184	0.430
9	rs3761847	1.090	0.981	1.210	0.108	1.075	0.958	1.207	0.217

Combined analysis of Stage 1 and Stage 2 data from individuals between 60 and 80 years of age was performed to clarify the association of rs2837960, rs3761847 and rs2002842 with AD risk. The only SNP found to retain a significant association with AD was rs2837960, the G allele of which appears to increase AD risk.