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Osteoblast-specific Capns1 knockout mutant mice showed reduced serum total osteocalcin (OCN) levels (A), which was mainly due to a significant reduction of uncarboxylated osteocalcin levels (B). Mutant mice had lower body weight (C) and were leaner (D) than control mice. The average food intake (E) and rectal temperature (F) of mutant mice were lower than those of control mice. *, p<0.05. **, p<0.005, ***, p<0.001.
