Table 1. Baseline clinical characteristics of participants.

	Severe sepsis	Non-severe sepsis	Controls	p value*
Subjects (n)	50	30	40
Age†	52 (48–57)	50 (46–55)	48 (44–52)	NS
Male – n (%)	29 (58%)	20 (67%)	27 (68%)	NS
Diabetic – n (%)	16 (32%)	7 (23%)	13 (33%)	NS
Mean Arterial Pressure‡	74 (70–82)n = 50	88 (77–104)n = 30	80 (73–93)n = 37	0.001
Systolic Blood Pressure‡	113 (105–132)n = 49	123 (110–140)n = 24	115 (110–128)n = 37	NS
Diastolic Blood Pressure‡	60 (54–68)n = 49	70 (60–90)n = 24	60 (60–75)n = 37	0.002
APACHE II‡	19 (15–23)	7 (5–12)		<0.0001
SOFA score (day 0)‡	6 (3–9)	1 (0–2)		<0.0001
RH-PAT index†	1.59 (1.45–1.73)n = 45	1.86 (1.67–2.05)n = 26	2.04 (1.91–2.18)n = 36	<0.0001
Causative Organism – n (%)				NS
None Cultured	23 (46%)	20 (67%)
Gram Positive Bacterium	14 (28%)	4 (13%)
Gram Negative Bacterium	13 (26%)	6 (20%)
Nutrition – n (%)
Oral feeding	29 (58%)	29 (97%)
Enteral feeding	16 (32%)	1 (3%)
Nil By Mouth	5 (10%)

*For difference between all 3 groups by one way analysis of variance.

†Mean (95% confidence interval).

‡Median (interquartile range).