Table 1. Fatty Acid Levels in Serum and Perigonadal Fat.
| SERUM | |||||
| Fatty Acids | Fatty Acid | HFD/Chow | HFD+ Leu/Chow | HFD/Chow | HFD+Leu/Chow |
| P-VALUE | P-VALUE | ||||
| Essential fatty acids | Docosapentaenoate (n3 DPA; 22:5n3) | 0.55 | 0.82 | 0.0001 | 0.1917 |
| Docosahexaenoate (DHA; 22:6n3) | 0.65 | 0.84 | 0.0000 | 0.0867 | |
| Long chain fatty acid | Palmitate (16:0) | 0.73 | 0.88 | 0.0001 | 0.1507 |
| Margarate (17:0) | 0.82 | 1.06 | 0.0224 | 0.5128 | |
| 10-heptadecenoate (17:1n7) | 0.67 | 0.85 | 0.0102 | 0.3118 | |
| Oleate (18:1n9) | 0.84 | 1.03 | 0.0297 | 0.7254 | |
| Linoleate (18:2n6) | 0.75 | 0.88 | 0.0004 | 0.1284 | |
| Nonadecanoate (19:0) | 0.68 | 0.95 | 0.0189 | 0.6420 | |
| 10-nonadecenoate (19:1n9) | 0.57 | 0.78 | 0.0009 | 0.2374 | |
| Eicosenoate (20:1n9 or 11) | 0.64 | 0.93 | 0.0053 | 0.6917 | |
| Dihomo-linoleate (20:2n6) | 1.34 | 1.79 | 0.0236 | 0.0001 | |
| Eicosatrienoate (20:3n9) | 1.96 | 3.05 | 0.0180 | 0.0000 | |
| Arachidonate (20:4n6) | 2.48 | 3.23 | 0.0000 | 0.0000 | |
| Adrenate (22:4n6) | 1.48 | 2.23 | 0.0024 | 0.0000 | |
Free Fatty Acids were analyzed by metabolomics in serum and fat from mice after 8 weeks on each diet. Essential, medium and long chain fatty acids are represented. Differences between HFD and CD as well as HFD + Leu and CD (ratios) are shown iserum (top panel) and perigonadal fat (bottom panel).