TABLE III.
Subject Number |
Age (years) |
Diagnosis | # days of therapy | DLT | Response | Note |
---|---|---|---|---|---|---|
1 | 9.6 | T cell | 6 | IE* | PD | |
2 | 9.4 | B-precursor | 28 | No | SD | |
3 | 5.2 | B-precursor | 4 | IE* | - | Found to have Ph+ ALL |
4 | 6.8 | B-precursor | 28 | No | CR | |
5 | 20.8 | T cell | 45 | No | SD | |
6 | 15.2 | B-precursor | 42 | No | SD | |
7 | 11.0 | B-precursor | 29 | No | SD | |
8 | 7.2 | B-precursor | 25 | No | PD | |
9 | 8.0 | B-precursor | 1 | Yes | - | Grade 4 infusion related toxicity lasting > 24 hrs |
10 | 3.2 | T cell | 1 | Yes | - | Grade 3 infusion related toxicity. Family withdrew |
11 | 7.2 | B-precursor | 4 | IE* | - | Incorrect doses administered |
12 | 4.4 | B-precursor | 25 | No | PD | |
13 | 9.2 | B-precursor | 18 | IE* | PD |
Patient not fully evaluable for toxicity if they received less than 85 % of the intended dose; IE, inevaluable; CR, complete remission; SD, stable disease; PD, progressive disease.