TABLE IV.
Toxicity Type | Course 1 (total, 9 courses) | |||
---|---|---|---|---|
Grade 1 | Grade 2 | Grade 3 | Grade 4 | |
Allergic reaction/hypersensitivity (including drug fever) | 1 | 2 | ||
Hypotension | 1 | |||
Fever (in the absence of neutropenia, where neutropenia is defined as ANC <1.0 × 10e9/L) |
3 | |||
Rigors/chills | 1 | 4 | ||
Rash/desquamation | 2 | |||
Diarrhea | 1 | |||
Febrile neutropenia (fever of unknown origin without clinically or microbiologically documented infection)(ANC <1.0 × 10e9/L, fever >=38.5 d |
1 | |||
Hypoalbuminemia | 2 | |||
ALT, SGPT | 1 | |||
AST, SGOT | 1 | |||
Hypocalcemia | 1 | |||
Hypercalcemia | 1 | |||
Hyperglycemia | 1 | |||
Hypomagnesemia | 1 | |||
Hypokalemia | 2 | |||
Hypernatremia | 1 | |||
Hyponatremia | 1 | |||
Pain Buttock | 1 | |||
Pain headache | 2 | |||
PAIN NOS | 1 | |||
Cough | 1 | |||
Edema, larynx | 1 | |||
Hypoxia | 1 |