Table 2.

Total and specific IgE levels in children with sickle cell anemia with and without asthma.

Variables	Asthma (n= 25)	Non-asthma (n=272)	P
Total IgE, mean (SD)	623 (941)	207 (339)	0.005
Food sensitization present n, (% of group) †	11 (61%)	63 (35%)	0.03
Respiratory sensitization present n, (% of group) ††	15 (79%)	92 (43%)	0.002

Mean IgE levels are shown and compared using a student t-test for children with and without asthma. The mean total IgE level significantly differed between children with and without asthma (p=0.005). A chi-square test was performed to evaluate the difference in specific IgE level in the presence or absence of a physician diagnosis of asthma. The proportion of children with food allergy or respiratory allergy is significantly different among asthma and non-asthma groups (P=0.03 and 0.002, respectively).

^†Food sensitization presence defined by positive Fx5c tests.

^††Respiratory sensitization presence defined by positive Phadiatop.