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. Author manuscript; available in PMC: 2012 Jul 1.
Published in final edited form as: Eur J Haematol. 2011 Jul;87(1):37–45. doi: 10.1111/j.1600-0609.2011.01615.x

Table 3.

PNH clone size change in five patients received HiCy only treatment, who first went in remission and then relapsed

Patient ID PNH clone size (%)change with time
during remission during relapse
2 0.84 (0.16 to 1) in 86 mos 49 (1 to 50) in 35 mos
4 1.02 (1.68+ to 2.7) in 30 mos 28.3 (2.7 to 31) in 53 mos
7 0.3 (0.1 to 0.4) in 53 mos 37.6 (0.4 to 38) in 56 mos
8 1.88 (0.12 to 2) in 38 mos 21 (2 to 23) in 14 mos
14 3 mos* 55.3 (28.7 to 84) in 12 mos
Mean±SD 1.01±0.7 in 51.8±24.7 mos 38.2±14.2 in 34±20.8 mos

P=0.029

*

no PNH size data available during those 3 months of remission period.

+

this patient's initial (treatment naïve) PNH granulocyte clone size was 24% (see table 2) and her initial post HiCy treatment PNH granulocyte clone size was 1.68%. Other 4 patients didn't have obvious PNH size change right after HiCy treatments, which might be due to their original PNH clone sizes were very small already.