Table 4.
Associations between variant ITGA2 genotypes and clinicopathological characteristics of gastric cancer1
| Variable | CT + TT | CC | Crude OR (95% CI) | P value | Adjusted OR2 (95% CI) | P value |
| Tumor differentiation | ||||||
| Well | 42 | 42 | 1 | 1 | ||
| Moderate | 65 | 69 | 0.94 (0.55-1.63) | 0.830 | 0.94 (0.54-1.63) | 0.828 |
| Poor | 55 | 27 | 2.04 (1.09-3.82) | 0.027 | 2.21 (1.12-4.38) | 0.022 |
| Depth of tumor infiltration | ||||||
| T1 | 24 | 30 | 1 | 1 | ||
| T2 | 21 | 17 | 1.54 (0.67-3.56) | 0.308 | 1.76 (0.73-4.25) | 0.208 |
| T3 | 34 | 40 | 1.06 (0.53-2.15) | 0.866 | 1.10 (0.52-2.32) | 0.797 |
| T4 | 83 | 51 | 2.03 (1.07-3.86) | 0.030 | 2.12 (1.10-4.07) | 0.024 |
| Lymph node metastasis | ||||||
| Negative | 59 | 51 | 1 | 1 | ||
| Positive | 103 | 87 | 1.02 (0.64-1.64) | 0.923 | 0.98 (0.61-1.58) | 0.942 |
| Localization | ||||||
| Cardia | 38 | 41 | 1 | 1 | ||
| Non-cardia | 128 | 100 | 1.38 (0.83-2.31) | 0.217 | 1.38 (0.81-2.35) | 0.231 |
1Data of seven plaintively treated cases were not obtained for the inoperable tumors;
2
Adjusted for age, sex, smoking status, residence, hypertension, and diabetes. OR: Odds ratio.