Table 2.
Univariate model of Cox and log normal regression with prognostic factors
|
HR (95% CI) |
||||
| Cox | Log normal | |||
| Sex | ||||
| Male | 0.953 (0.843-1.078) | 0.925 (0.818-1.046) | ||
| Female | 1.00 | 1.00 | ||
| Age at diagnosis | 1.0151 (1.009-1.020) | 1.0161 (1.011-1.021) | ||
| Past history | ||||
| Without | 1.00 | 1.00 | ||
| With | 0.7151 (0.631-0.831) | 0.6941 (0.612-0.787) | ||
| Family history | ||||
| Without | 1.00 | 1.00 | ||
| With | 0.871 (0.752-1.009) | 0.875 (0.754-1.014) | ||
| Cancer number | ||||
| Single | 1.00 | 1.00 | ||
| Multiple | 0.870 (0.622-1.218) | 0.924 (0.661-1.294) | ||
| Cancer location | ||||
| Lower third | 1.00 | 1.00 | ||
| Middle third | 1.1811 (1.017-1.373) | 1.3021 (1.233-1.374) | ||
| Upper third | 1.4361 (1.212-1.701) | 1.6951 (1.429-1.897) | ||
| Total stomach | 2.4641 (2.062-2.944) | 2.2071 (2.011-2.677) | ||
| Distant metastasis | ||||
| Absent | 1.00 | 1.00 | ||
| Present | 2.5541 (2.194-2.973) | 2.5961 (2.227-3.027) | ||
| Surgical curative degree | ||||
| Absolutely radical | 1.00 | 1.00 | ||
| Relatively radical | 1.8351 (1.593-2.114) | 2.1591 (2.020-2.308) | ||
| Palliative | 4.2361 (3.714-4.832) | 4.6611 (4.214-4.759) | ||
| Lymph node dissection | ||||
| > D2 | 1.00 | 1.00 | ||
| D2 | 0.989 (0.859-1.138) | 1.5361 (1.458-1.619) | ||
| D1 | 1.056 (0.853-1.307) | 2.3591 (2.121-2.574) | ||
| < D1 | 3.3101 (2.854-3.839) | 3.6241 (3.231-3.862) | ||
| Combined other organ resection | ||||
| Without | 1.00 | 1.00 | ||
| With | 1.9811 (1.749-2.245) | 2.0701 (1.825-2.348) | ||
| Histologic types | ||||
| Well differentiated | 1.00 | 1.00 | ||
| Middle differentiated | 0.7061 (0.592-0.843) | 0.976 (0.918-1.039) | ||
| Poor differentiated | 0.918 (0.814-1.036) | 0.952 (0.897-1.011) | ||
| Borrmann classification (n (%)) | ||||
| I | 1.00 | 1.00 | ||
| II | 1.005 (0.892-1.340) | 0.981 (0.894-1.019) | ||
| III | 1.2471 (1.173-1.638) | 1.1761 (1.074-1.293) | ||
| IV | 2.5121 (1.842-3.075) | 2.6101 (2.416-3.153) | ||
| Lauren classification (n (%)) | ||||
| Intestinal type | 1.00 | 1.00 | ||
| Diffuse type | 1.2451 (1.082-1.184) | 1.1711 (1.015-1.384) | ||
| pT stage | ||||
| pT1 | 1.00 | 1.00 | ||
| pT2 | 2.9361 (2.299-3.751) | 1.7871 (1.666-1.916) | ||
| pT3 | 4.3051 (3.357-5.522) | 3.1931 (3.066-3.321) | ||
| pT4 | 7.6971 (5.759-10.287) | 5.7071 (5.579-5.833) | ||
| Total dissected nodes | 0.9931 (0.988-0.998) | 0.9941 (0.988-0.998) | ||
| pN stage | ||||
| pN0 | 1.00 | 1.00 | ||
| pN1 | 1.5551 (1.372-1.764) | 1.6331 (1.533-1.740) | ||
| pN2 | 2.5101 (2.133-2.953) | 2.6671 (2.561-2.772) | ||
| pN3 | 3.6691 (2.901-4.640) | 4.3551 (4.249-4.460) | ||
1
Statistically significant (P < 0.05). HR: Hazard radio; CI: Confidence interval.