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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: Mol Cell Neurosci. 2011 Apr 2;47(2):137–144. doi: 10.1016/j.mcn.2011.03.009

Fig. 7.

Fig. 7

ERK-dependent signalling during conditioning and extinction of fear. Conditioning involves the ERK/MSK/RSK/c-Fos pathway. Extinction, on the other hand, induces nuclear pERK/c-Jun interactions and increases the inhibitory AP-1 complexes JunD and JDP2. The later changes may be involved, at least in part, in the down-regulation of c-Fos and GluR2.