Table 2.
Correlation Between Change in MGH-SFI Item Scores and Change in MADRS Total Score and Prolactin Level (safety sample)a
| Change inMADRS Total Score | Change in Prolactin Level | |||
| Correlation | Adjunctive Placebo | Adjunctive Aripiprazole | Adjunctive Placebo | Adjunctive Aripiprazole |
| Total population | ||||
| Interest in sex | 0.217 | 0.211 | −0.064 | −0.091 |
| Sexually aroused | 0.185 | 0.219 | −0.053 | −0.008 |
| Achieve orgasm | 0.168 | 0.193 | −0.059 | −0.073 |
| Sexual satisfaction | 0.167 | 0.241 | −0.065 | −0.099 |
| Overall improvement | 0.301 | 0.372 | −0.069 | −0.069 |
| Females | ||||
| Interest in sex | 0.196 | 0.194 | −0.065 | −0.064 |
| Sexually aroused | 0.184 | 0.227 | −0.063 | −0.001 |
| Achieve orgasm | 0.170 | 0.195 | −0.085 | −0.024 |
| Sexual satisfaction | 0.148 | 0.208 | −0.074 | −0.063 |
| Overall improvement | 0.253 | 0.375 | −0.091 | −0.019 |
| Males | ||||
| Interest in sex | 0.276 | 0.224 | −0.049 | −0.100 |
| Sexually aroused | 0.186 | 0.179 | 0.029 | 0.085 |
| Achieve orgasm | 0.157 | 0.152 | 0.118 | −0.145 |
| Maintain erection | 0.160 | 0.152 | −0.007 | 0.070 |
| Sexual satisfaction | 0.223 | 0.295 | −0.001 | −0.101 |
| Overall improvement | 0.416 | 0.327 | 0.038 | −0.064 |
Bolded values represent P<.05.
Abbreviations: MADRS=Montgomery-Asberg Depression Rating Scale, MGH-SFI=Massachusetts General Hospital-Sexual Functioning Inventory.