Figure 5.
Kif4A depletion led to reduced homologous recombination in cells. (A) Time scheme for the transfection of Kif4A shRNA and I-SceI expression plasmids. (B) Percentage of GFP positive population detected by FACS analysis with samples collected at 12, 24 or 48 hours after 2nd Kif4A shRNA/I-SceI expression. The results were showed separately in a histogram (C). (D) cell cycle profiles of cells harvested at 24, 48 or 72 hours after Kif4A shRNA transfection (with I-SceI co-transfected at 48 hrs) as in (A).