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. 2011 Mar 22;173(10):1121–1130. doi: 10.1093/aje/kwq497

Table 2.

Simulated Pandemic Influenza A (H1N1) Illness Attack Rates and Numbers of Cases, Hospitalizations, and Deaths for Los Angeles County and the Continental United States in 3 Scenariosa

Measure and Scenario Los Angeles Countyb
Continental United Statesc
Childrend
Adultsd
Total
Children
Adults
Total
% Mean Range % Mean Range % Mean Range % Mean Range % Mean Range % Mean Range
Illness attack rate
    No vaccination 36.2 15.4 21.4 35.6 15.8 21.5
    Vaccination 32.2 13.0 18.5 31.1 13.4 18.5
    Early vaccination 23.9  9.4 13.5 23.8 10.0 14.0
No. of cases
    No vaccination 1.15M 0.82M–1.69M 1.22M 0.87M–1.79M 2.37M 1.69M–3.48M 27.9M 19.9M–41.0M 36.0M 25.6M–52.8M 63.9M 45.5M–93.8M
    Vaccination 1.02M 0.73M–1.50M 1.03M 0.73M–1.51M 2.05M 1.46M–3.02M 24.4M 17.4M–35.8M 30.7M 21.8M–45.1M 55.1M 39.2M–80.9M
    Early vaccination 0.76M 0.54M–1.12M 0.74M 0.53M–1.09M 1.50M 1.07M–2.21M 18.7M 13.3M–27.4M 22.8M 16.2M–33.5M 41.5M 29.5M–60.9M
    CDC estimatese 19.5M 13.9M–28.6M 41.3M 29.4M–60.7M 60.8M 43.3M–89.3M
No. of deaths
    No vaccination 68 48–100 338 240–496 406 289–596 1,790 1,270–2,630 10,200 7,260–15,000 12,000 8,540–17,600
    Vaccination 56 40–82 266 189–391 322 229–473 1,540 1,090–2,260 8,610 6,120–12,600 10,100 7,220–14,900
    Early vaccination 38 27–56 177 126–260 215 153–316 1,160 821–1,700 6,280 4,460–9,210 7,430 5,280–10,900
    CDC estimates 1,280 912–1,880 11,200 7,960–16,400 12,500 8,870–18,300
No. of hospitalizations
    No vaccination 4,690 3,340–6,890 5,640 4,010–8,280 10,300 7,350–15,200 0.12M 0.09M–0.18M 0.17M 0.12M–0.25M 0.29M 0.21M–0.43M
    Vaccination 3,810 2,710–5,600 4,450 3,170–6,540 8,270 5,880–12,100 0.11M 0.07M–0.15M 0.14M 0.10M–0.21M 0.25M 0.18M–0.37M
    Early vaccination 2,630 1,870–3,870 2,970 2,110–4,350 5,600 3,980–8,220 0.08M 0.06M–0.12M 0.11M 0.07M–0.15M 0.18M 0.13M–0.27M
    CDC estimates 0.09M 0.06M–0.13M 0.19M 0.13M–0.28M 0.27M 0.20M–0.40M

Abbreviations: CDC, Centers for Disease Control and Prevention; M, million.

a

The 3 scenarios were: baseline (no vaccination), vaccination (vaccination begins in early October), and early vaccination (vaccination begins in early September).

b

Results for Los Angeles County are averages from 5 runs.

c

Results for the United States are from a single stochastic run from simulations based on the 2000 US Census (http://www.census.gov/geo/www/cenpop/tract/tract_pop.txt), adjusted to the 2009 US population.

d

Children were defined as persons aged 18 years or younger, while adults were those aged 19 years or older.

e

Estimates for the United States were obtained from the CDC (3).