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Cytotoxicity of HDACI in different cells
| HDACI | CC50 (μm) |
|||
|---|---|---|---|---|
| Jurkata | HeLaa | 293Ta | CD8(+)-depleted PBMCb | |
| Apicidin | 10.0 ± 0.1 | 11.3 ± 1.7 | 12.2 ± 1.4 | 0.1 |
| Oxamflatin | 5.9 ± 0.1 | 9.4 ± 0.8 | 6.0 ± 1.0 | 0.3 |
| SAHA | 10.0 ± 0.1 | 11.3 ± 0.3 | 14.1 ± 0.2 | 7.5 |
| Scriptaid | 6.1 ± 0.3 | 8.9 ± 1.8 | 5.8 ± 0.2 | 0.7 |
a Data represent the mean ± S.D. from three replicate experiments.
b Data represent the mean from two independent replicate experiments.
