FIGURE 2.

Oxygen consumption by osteosarcoma cells is significantly decreased. A, a graphic representation of the oxygen consumption rate is shown. 600,000 cells were suspended in 300 μl of medium at 37 °C in a sealed chamber, and oxygen consumption (Vresp.) was measured for 15 min with a Clark-type electrode. B, respiratory capacity of the cells as expressed in nmol of oxygen/min/1 million cells is shown. Values represent the means ± S.E.; n = 3 independent measurements. *, p < 0.05, as compared with hFOB cells.