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Model for the Delivery of Ciliary Proteins. Our data support a model in which the exocyst complex is targeted to the primary cilium by Cdc42 and is then stabilized by binding to the Par complex via Par6. Once the exocyst complex is stabilized at the primary cilium, it then targets and docks vesicles carrying ciliary proteins, such as polycystin-2, by interacting with Rab8 found on the vesicles..
