TABLE 2.
Inhibition of CaMKKβ by STO-609
| STO-609 | Phosphorylation activity (nmol/min/nmol CaMKKβ) |
% of inhibition | |
|---|---|---|---|
| 0 μm | 0.5 μm | ||
| CaMKKβ KD | 7.52 ± 0.48 | 2.96 ± 0.40 | 60.7 ± 2.8 |
| CaMKKβ | 1.22 ± 0.17 | 0.502 ± 0.001 | 58.5 ± 5.7 |
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