TABLE 3.
Mutants | Binding to LPS |
Binding to LTA |
Binding to PGN |
|||
---|---|---|---|---|---|---|
Kd | Bmax | Kd | Bmax | Kd | Bmax | |
μg/ml | ng/pmol | μg/ml | ng/pmol | μg/ml | ng/pmol | |
m1 | 1.1 | 5.9 | 1.3 | 6.0 | 1.5 | 6.3 |
m3 | 1.1 | 6.0 | 1.3 | 6.1 | 1.6 | 6.3 |
m5 | 1.1 | 5.8 | 1.3 | 5.9 | 1.6 | 6.1 |
m7 | 1.2 | 5.8 | 1.2 | 5.8 | 1.6 | 6.1 |
m9 | 1.2 | 5.7 | 1.3 | 5.9 | 1.7 | 6.1 |
m12 | 2.3 | 2.4 | 2.2 | 2.5 | 2.7 | 2.4 |
m13 | 2.8 | 2.1 | 2.6 | 2.1 | 3.0 | 2.2 |