TABLE 2.
Overrepresented biological annotation terms
| Category | Term | Number of genes (up/down) | Fold enrichment | BH P value |
|---|---|---|---|---|
| GO_BP | Cell cycle | 191 (126/65) | 1.45 | 2.10E-05 |
| GO_BP | Lipid metabolic process | 172 (119/53) | 1.47 | 2.40E-05 |
| GO_BP | Vesicle-mediated transport | 126 (67/59) | 1.55 | 3.20E-05 |
| GO_BP | Response to stress | 200 (129/71) | 1.34 | 9.36E-04 |
| GO_BP | Cell adhesion | 164 (70/94) | 1.36 | 2.14E-03 |
| GO_BP | Axonogenesis | 52 (7/45) | 1.72 | 5.55E-03 |
| GO_BP | Apoptosis | 160 (99/61) | 1.31 | 1.29E-02 |
| GO_BP | Lipid transport | 30 (22/8) | 1.82 | 2.27E-02 |
| GO_BP | Carbohydrate metabolic process | 100 (76/24) | 1.2 | 5.24E-02 |
| GO_CC | Axon | 33 (6/27) | 1.95 | 2.31E-02 |
| GO_CC | Mitochondrion | 227 (175/52) | 1.91 | 5.24E-02 |
Functional terms significantly overrepresented in the DEGs are listed. BH P value, Benjamini-Hochberg corrected P value of enrichment in DAVID; GO_BP, GO biological process; GO_CC, GO cellular component.