TABLE 3.
TnT | TnI | pCa50 | ΔpCa50a | Hill coefficient, nH | % Maximal force | % Ca2+ unregulated force | No. experiments |
---|---|---|---|---|---|---|---|
HCTnT3-WT | HCTnI | 5.67 ± 0.01 | 2.83 ± 0.12 | 50.81 ± 3.36 | 90.30 ± 2.75 | 12 | |
HCTnT3-ΔN100/ΔE101 | HCTnI | 5.86 ± 0.02b | +0.19 | 1.94 ± 0.09b | 51.30 ± 2.90 | 91.79 ± 3.95 | 10 |
HCTnT3-ΔN100 | HCTnI | 5.96 ± 0.03b | +0.29 | 1.84 ± 0.08b | 54.73 ± 3.09 | 93.77 ± 3.03 | 13 |
HCTnT3-ΔE101 | HCTnI | 5.39 ± 0.01b | −0.28 | 3.14 ± 0.32 | 28.40 ± 1.98b | 99.33 ± 0.45b | 8 |
HCTnT1-WT | HSSTnI | 5.78 ± 0.02 | 2.05 ± 0.11 | 44.43 ± 1.56 | 96.46 ± 1.62 | 11 | |
HCTnT1-ΔN110/ΔE111 | HSSTnI | 5.82 ± 0.02 | +0.04 | 2.11 ± 0.05 | 55.12 ± 3.08b | 87.60 ± 3.76b | 8 |
HCTnT1-ΔN110 | HSSTnI | 5.82 ± 0.03 | +0.04 | 2.40 ± 0.10 | 56.02 ± 2.09b | 88.42 ± 4.22b | 6 |
HCTnT1-ΔE111 | HSSTnI | 5.49 ± 0.04b | −0.29 | 2.83 ± 0.33 | 21.83 ± 4.30b | 95.13 ± 2.29 | 6 |
a TnT3-RCM pCa50 − TnT3-WT pCa50 or TnT1-RCM pCa50 −TnT1-WT pCa50.
b p < 0.05.