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PP1 is inactivated in Egr-1-overexpressing rat hippocampus. Extracts of the indicated virus-injected rat hippocampus were subjected to Western blotting using the indicated antibodies. Based on the band intensities, the relative amounts of various proteins on the blot were determined. A, Western blots. B, relative amounts. The values are the mean ± S.E. from three hippocampal extracts in each group. *, p > 0.005 (t test). pPP1, phosphorylated PP1; pPP2A, phosphorylated PP2A.
